Drug Discovery & Development Platform
Using a multi-disciplinary approach to mine and validate novel therapeutic products identified in our microbiome profiling databases.
Through Second Genome’s proprietary platform, we are turning microbial genetics into medicines. Built with innovative technologies, including machine-learning analytics, customized protein engineering techniques, phage library screening, mass spec analysis and CRISPR, the platform enables Second Genome to identify genes and biomarkers, find bacterial proteins of interest and identify human drug targets. By coupling these insights with traditional drug development approaches, we, and our strategic partners, are able to progress development of therapies and companion diagnostics for wide-ranging diseases.
Disease Focus Areas
This approach is based on understanding microbial community composition and its function in healthy and diseased conditions. Our powerful data analysis techniques enable the rapid identification of microbes and microbial biomarkers that influence a given disease state. Combined with our expertise in drug development, our team has built the foundation for the rapid discovery of new therapeutic options for patients in a numerous microbiome-related diseases.
Drug Discovery Platform
Second Genome has assembled a one-of-a-kind drug discovery platform that integrates microbiome and host biology for the identification of novel targets and drugs. Built from the ground up by microbiome information experts, our platform delivers a computational pipeline of potential therapeutic bioactive molecules for assay evaluation.
Microbiome to Medicine™
Recent scientific discoveries related to the microbiome are forcing the industry to rethink how changes in the microbiome influence human health. Research makes clear that changes in the microbiome can cause changes to human cellular activities that result in disease or contribute to its progression.
Microbiome Technologies
Second Genome’s microbiome discovery platform allows us to generate and evaluate small molecules, peptide biologic and bacterial strains that modulate microbe-human interactions. By integrating our in vivo models with our in silico analyses we are able to understand how these compounds improve health and eliminate disease. These technologies allow our research team to identify key microbial community members, and bioactive molecules.